The chaos began when a package exploded at a home in the city's Windsor neighborhood at about 6:45 a.m., Austin police said.
The package was brought inside the house, and it detonated as it was being opened, police said.
The blast killed a 17-year-old boy, and sent a woman in her 40s to the hospital with non-life-threatening injuries, Austin Police Chief Brian Manley told reporters earlier Monday.
Police then received multiples calls after 11:50 a.m. about an explosion at a home in the Montopolis neighborhood.
First responders, fire officials and police responded to the scene where they found an injured 75-year-old Hispanic woman.
Similar to Monday's bombing and a March 2 explosion that killed 39-year-old Anthony Stephan House, the woman picked up a package that was left outside her home before it detonated, Manley said.
The woman was hospitalized in critical but stable condition, and her injuries are life threatening.
Authorities haven't released the victims' identities. Manley said it's unknown if the victims were intended targets.
The two victims killed in separate explosions are African-Americans. Cops aren't ruling out whether the bombings were hate crimes.
Manley urged residents to remain vigilant and to alert the police about suspicious packages delivered to their home.
"If you receive a package that you are not expecting or looks suspicious, DO NOT open it, call 911 immediately," the chief tweeted.
The third package didn't come through the mail and someone possibly dropped it at the house overnight.
"We do not believe at all that this was a delivery that came through the postal service," Manley said. "So it was placed on the front door step."
The FBI and Bureau of Alcohol, Tobacco, Firearms and Explosives, and the U.S. Postal Service are investigating the incidents.
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