Honda says collaboration with the Google unit called Waymo would let researchers learn about integration of sensors, software and computers.
The automaker says that if a deal is reached, it will provide vehicles to Waymo that are modified to handle the technology. The Hondas would join Waymo's fleet that includes Lexus SUVs and Chrysler Pacifica minivans.
Honda has said it intends to put autonomous vehicles on highways around 2020.
The potential partnership would be the latest in a flurry of autonomous vehicle deals recently between technology companies and automakers.
Google has been working on software and sensors since 2009 and has been testing autonomous cars on public roads for several years.
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