The virus does not affect 32-bit operating systems such as Windows 2000 or Windows XP unless the operating system is emulating a 64-bit environment. When W64.Shruggle.1318 is executed, it searches 64-bit executable files that are in same folder, and all subfolders, as the one from which the virus was executed. When it finds a 64-bit executable file, the virus appends itself to the file, including .dll files.
W64.Shruggle will be the first virus to test AMD's new processor, which the company claims helps stop viruses from infecting a system.