There will be plenty of impacts to small businesses that feed off of these companies. Amazon has 50,000 employees in Seattle, primarily concentrated in one campus like area of the city. They have 47 buildings in downtown Seattle. The restaurants, food trucks and other vendors who cater to these thousands of employees will have trouble surviving until their customers return.
For the longer term, building owners and operators, developers and construction companies are likely eyeing these changes warily. What will this mass migration of employees of large businesses to home mean for their own futures?